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Nano-Bio Engineering Group

   

 

 Amir Shamloo, Associate Professor

 

Mechanical Engineering Department, Sharif University of Technology

 

Ph.D, Stanford University, 2010

 

Postdoc, University of California, Berkeley, 2010-2011

Research Interests

 

Design and Application of Microfluidics Devices

Modeling, Design and Fabrication of Nano-Mechanical Structures

Molecular Dynamic Simulation

Tissue Engineering and Biomaterials-Stem Cell Interactions

Computational Analysis of Biological Systems and Cell Mechanics

Finite Element Modeling of Elasto-Plastic Materials

 

Teaching Interests

 

Fluid Mechanics I

Fluid Mechanics II

Advanced Mathematics

Advanced Fluid Mechanics

Principles of Bioengineering

Applied Nanotechnology

 

Selected Publications

Shamloo, A., A. Selahi, and M. Madadelahi, Designing and modeling a centrifugal microfluidic device to separate target blood cells. Journal of Micromechanics and Microengineering, 2016. 26(3): p. 035017.

 

Shamloo, A. and M. Sarmadi, Investigation of the adhesive characteristics of polymer–protein systems through molecular dynamics simulation and their relation to cell adhesion and proliferation. Integrative Biology, 2016. 8(12): p. 1276-1295.

 

Shamloo, A., P. Vatankhah, and M.A. Bijarchi, Numerical optimization and inverse study of a microfluidic device for blood plasma separation. European Journal of Mechanics-B/Fluids, 2016. 57: p. 31-39.

 

Shamloo, A., et al., Computing the blood brain barrier (BBB) diffusion coefficient: A molecular dynamics approach. Journal of Magnetism and Magnetic Materials, 2016. 410: p. 187-197.

 

Shamloo, A., et al., A comparative study of collagen matrix density effect on endothelial sprout formation using experimental and computational approaches. Annals of biomedical engineering, 2016. 44(4): p. 929-941.

 

Shamloo, A., M. Mirzakhanloo, and M.R. Dabirzadeh, Numerical Simulation for efficient mixing of Newtonian and non-Newtonian fluids in an electro-Osmotic Micro-Mixer. Chemical Engineering and Processing: Process Intensification, 2016.

 

Shamloo, A., A. Merdasi, and P. Vatankhah, Numerical Simulation of Heat Transfer in Mixed Electroosmotic Pressure-Driven Flow in Straight Microchannels. Journal of Thermal Science and Engineering Applications, 2016. 8(2): p. 021011.

 

Shamloo, A., M. Madadelahi, and A. Akbari, Numerical simulation of centrifugal serpentine micromixers and analyzing mixing quality parameters. Chemical Engineering and Processing: Process Intensification, 2016. 104: p. 243-252.

 

Sarvestani, A.N., A. Shamloo, and M.T. Ahmadian, Simulation of Paramecium Chemotaxis Exposed to Calcium Gradients. Cell biochemistry and biophysics, 2016: p. 1-12.

 

Moradi, M., A. Shamloo, and A.D. Dezfuli, A sequential implicit discrete fracture model for three-dimensional coupled flow-geomechanics problems in naturally fractured porous media. Journal of Petroleum Science and Engineering, 2016.

 

Pedram, M.Z., A. Shamloo, et al., Dynamic Analysis of Magnetic Nanoparticles Crossing Cell Membrane. Journal of Magnetism and Magnetic Materials, 2016.

 

Pedram, M.Z., A. Shamloo, et al., Optimal Magnetic Field for Crossing Super-Para-Magnetic Nanoparticles through the Brain Blood Barrier: A Computational Approach. Biosensors, 2016. 6(2): p. 25.

 

Kiyoumarsioskouei, A., A. Shamloo, et al., A computational model for estimation of mechanical parameters in chemotactic endothelial cells. Scientia Iranica. Transaction B, Mechanical Engineering, 2016. 23(1): p. 260.

 

Heidari, H. and A. Shamloo, The effect of rippled graphene sheet roughness on the adhesive characteristics of a collagen–graphene system. International Journal of Adhesion and Adhesives, 2016. 64: p. 9-14.

 

Mohseni, M., A. Shamloo, et al., Antimicrobial Wound Dressing Containing Silver Sulfadiazine With High Biocompatibility: In Vitro Study. Artificial organs, 2016.

 

Esmaeili, E., A. Shamloo, et al., Dual improvement of DNA-directed antibody immobilization utilizing magnetic fishing and a polyamine coated surface. RSC Advances, 2016. 6(112): p. 111210-111216.

 

Shamsi, A., A. Shamloo, et al., High throughput blood plasma separation using a passive PMMA microfluidic device. Microsystem Technologies, 2015: p. 1-8.

 

Shamloo, A., et al., Performance optimization of microreactors by implementing geometrical and fluid flow control in the presence of electric field: a computational study. Microsystem Technologies, 2015. 21(6): p. 1275-1285.

 

Shamloo, A., N. Mohammadaliha, and M. Mohseni, Integrative utilization of microenvironments, biomaterials and computational techniques for advanced tissue engineering. Journal of biotechnology, 2015. 212: p. 71-89.

 

Shamloo, A., A. Golgoon, and E.G. Zadeh. Role of α and β Transmembrane Domains in Integrin Clustering. in Actuators. 2015. Multidisciplinary Digital Publishing Institute.

 

Shamloo, A., F. Manuchehrfar, and H. Rafii-Tabar, A viscoelastic model for axonal microtubule rupture. Journal of biomechanics, 2015. 48(7): p. 1241-1247.

 

Shamloo, A. and L. Amirifar, A microfluidic device for 2D to 3D and 3D to 3D cell navigation. Journal of Micromechanics and Microengineering, 2015. 26(1): p. 015003.

 

Shamloo, A., M. Heibatollahi, and M.R. Mofrad, Directional migration and differentiation of neural stem cells within three-dimensional microenvironments. Integrative Biology, 2015. 7(3): p. 335-344.

 

Pedram, M.Z., A. Shamloo, et al. Superparamagnetic Nanoparticles for Epilepsy Detection. in World Congress on Medical Physics and Biomedical Engineering, June 7-12, 2015, Toronto, Canada. 2015. Springer.

 

Abeddoust, M. and A. Shamloo, A model for cell density effect on stress fiber alignment and collective directional migration. Physical biology, 2015. 12(6): p. 066023.

 

Pedram, M.Z., A. Shamloo, et al., Toward Epileptic Brain Region Detection Based on Magnetic Nanoparticle Patterning. Sensors, 2015. 15(9): p. 24409-24427.

 

Shamloo, A., et al. Homo-oligomerization of transmembrane α-domain of integrin. in 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 2014. IEEE.

 

Shamloo, A., Cellcell interactions mediate cytoskeleton organization and collective endothelial cell chemotaxis. Cytoskeleton, 2014. 71(9): p. 501-512.

 

Shamloo, A., et al., Complex chemoattractive and chemorepellent Kit signals revealed by direct imaging of murine mast cells in microfluidic gradient chambers. Integrative Biology, 2013. 5(8): p. 1076-1085.

 

Shamloo, A., M. Heibatollahi, and E. Ghafar-Zadeh. Parallel in-vitro and in-vivo techniques for optimizing cellular microenvironments by implementing biochemical, biomechanical and electromagnetic stimulations. in 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 2012. IEEE.

 

Shamloo, A., H. Xu, and S. Heilshorn, Mechanisms of vascular endothelial growth factor-induced pathfinding by endothelial sprouts in biomaterials. Tissue Engineering Part A, 2011. 18(3-4): p. 320-330.

 

Shamloo, A., et al., Novel Receptor-Mediated Endothelial Cell Chemotaxis. Biophysical Journal, 2010. 98(3): p. 497a.

 

Shamloo, A. and S.C. Heilshorn, Matrix density mediates polarization and lumen formation of endothelial sprouts in VEGF gradients. Lab on a Chip, 2010. 10(22): p. 3061-3068.

 

Shamloo, A. and S.C. Heilshorn. The Interplay Between Biomechanical and Biochemical Factors Regulates Lumen Formation and Navigation of Endothelial Cell Sprouts. in ASME 2010 Summer Bioengineering Conference. 2010. American Society of Mechanical Engineers.

 

Shamloo, A. and S.C. Heilshorn, Matrix Rigidity Mediates Growth Factor Response during 3D Endothelial Cell Sprouting. Biophysical Journal, 2010. 98(3): p. 730a.

 

Kuhnert, F., A. Shamloo, et al., Essential regulation of CNS angiogenesis by the orphan G protein–coupled receptor GPR124. Science, 2010. 330(6006): p. 985-989.

 

Shamloo, A., et al., Endothelial cell polarization and chemotaxis in a microfluidic device. Lab on a chip, 2008. 8(8): p. 1292-1299.

 

Shamloo, A., M. Abeddoust, and N. Mehboudi, MICROFLUIDIC DEVICES AS IN VITRO MICROENVIRONMENTS FOR-STEM CELL CULTURE.

 

Mohseni, M., A. Shamloo, et al., PLAQUE STRUCTURE AFFECTS MECHANICAL STRESS DISTRIBUTION WITHIN BLOOD VESSELS.

 

Khoei, A., A. Shamloo, and A. Azami, Extended finite element method in plasticity forming of powder compaction with contact friction. International Journal of Solids and Structures, 2006. 43(18): p. 5421-5448.

 

Khoei, A., A. Shamloo, et al., The extended finite element method (X-FEM) for powder forming problems. Journal of materials processing technology, 2006. 177(1): p. 53-57.

 

Shamloo, A., A. Azami, and A. Khoei, Modeling of pressure-sensitive materials using a cap plasticity theory in extended finite element method. Journal of materials processing technology, 2005. 164: p. 1248-1257.

 

Conference and Symposia Presentations

 

Pedram, M.Z., A. Shamloo, et al. MRI-guided epilepsy detection. in 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). 2015. IEEE.

 

Khoei, A., A. Shamloo, et al. An Enriched Finite Element Modeling for Metal Forming Processes. in Proceedings of the International MultiConference of Engineers and Computer Scientists. 2008. Citeseer.

 

Manuchehrfar, F., A. Shamloo, and N. Mehboudi. Dynamic response of axonal microtubules under suddenly applied end forces. in 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 2014. IEEE.

 

Mohseni, A. Shamloo,  M., et al. Thickness as an important parameter in designing vascular grafts. in Biomedical Engineering (ICBME), 2014 21th Iranian Conference on. 2014. IEEE.

 

Manuchehrfar, F. and A. Shamloo. Three dimensional modeling of axonal microtubules. in Biomedical Engineering (ICBME), 2014 21th Iranian Conference on. 2014. IEEE.

 

Shamloo, A. Neuronal cell navigation within a microfluidic device. in 2nd Middle East Conference on Biomedical Engineering. 2014. IEEE.

 

Shamloo, A., E. GhafarZadeh, and A. Alasty. Modeling and simulation of crossing magnetic nanoparticles through Blood Brain Barrier (BBB). in 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 2014. IEEE.

 

Pedram, M.Z., A. Shamloo, et al. Steered Molecular Dynamic Simulation Approaches for computing the Blood Brain Barrier (BBB) Diffusion Coefficient. in World Congress on Medical Physics and Biomedical Engineering, June 7-12, 2015, Toronto, Canada. 2015. Springer.

 

Shamloo A, Heilshorn SC. Microfluidic Platforms for Study of 3D Cell Chemotaxis within Biomaterials. MRS Fall Meeting,

Boston, MA, December 2011.

 

Shamloo A, Nguyen CH, Manchandia MD, Weinberg K, Heilshorn SC. Paradoxical dose-dependent

chemoattractive and chemorepellent effects of Kit ligand (KL) revealed in novel microfluidic

biochambers. Society of Hematology conference, Orlando, FL, December 2010.

 

Shamloo A, Heilshorn SC. The interplay between biomechanical and biochemical factors regulates

lumen formation and navigation of endothelial cell sprouts, ASME summer bioengineering

conference, Naples, FL, June 2010.

 

    Shamloo A, Heilshorn SC. A three-dimensional micro-environment for characterizing endothelial cell

    sprouting, Society for Biomaterials, Seattle, WA, April 2010.

 

    Shamloo A, Heilshorn SC. Microfluidic models of endothelial cell sprouting in response to

    biomechanical and biochemical Microenvironments, AVS Symposium, San Jose, CA, Nov 2009.

 

Shamloo A, Heilshorn SC. Matrix rigidity mediates growth factor response during 3D endothelial

cell sprouting, 2009 Joint ASCE-ASME-SES Conference on Mechanics and Materials, Blacksburg,

VA, June 2009.

 

Shamloo A, Khoei. AR, Application of extended finite element method (XFEM) in double-surface

plasticity model, 1st National Congress on Civil Engineering (NCCE), Tehran, Iran, May 2004.

 

Shamloo A, Heilshorn SC. Novel receptor –mediated endothelial cell chemotaxis, Biophysical

Society, San Francisco, CA, Feb. 2010.

 

Shamloo A, Heilshorn SC. Concentration gradient generation for mammalian cell culture using a novel

microfluidic device. Nanotech 2008 - 11th Annual NSTI Nanotechnology, Boston, MA, June 2008.

 

Shamloo A, Heilshorn SC. A shear-free microfluidic device for mammalian cell chemotaxis. Bio-X

Interdisciplinary Initiatives, Stanford, CA, Feb 2008.

 

Shamloo A, Heilshorn SC. A novel microfluidic device for endothelial cell chemotaxis. Cardiovascular

Institute Retreat, Stanford, CA, Feb 2008.

 

Khoei AR, Shamloo A, Anahid M, Shahim K, The extended finite element method (X-FEM) for

powder forming problems, 11th International Conference on Metal Forming, Birmingham, UK, Sep

2006.

 

Shamloo A, Azami AR, Khoei AR, Modeling of pressure-sensitive materials using a cap plasticity

theory in extended finite element method, International Conference on Advances in Materials and

Processing Technologies (AMPT), Gliwice, Poland, May 2005.

 

Khoei AR, Shamloo A, Implementation of extended finite element method in pressure-sensitive

material using cap plasticity model, 3rd International Conference on Advances in Structural 

Engineering and Mechanics (ASEM), Seoul, Korea, September 2004.